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Application Notes
Lignin is an abundant phenylpropanoid polymer found in all plant matter. It has historically been treated as an impurity in the paper pulping and ethanol biorefinery industries where it is burned as a low-value fuel or sold at low prices. However, developing higher-value applications of lignin would help biorefineries operate at higher efficiencies. In this app note, a two-dimensional separation is conducted using centrifugal partition chromatography (CPC), which helps demonstrate the value of CPC as a tool for gaining deeper insights into depolymerization mixtures for biomass facilities.
The vinegar fly, or fruit fly, is an excellent animal model for studying the underlying mechanisms of human disease. In preparation for use in research studies, fruit fly larvae must eat and grow continuously over a four-day period before hatching. In this app note, we describe the time-consuming and labor-intensive process of preparing vessels with fly food and how to avoid it using a fully automated system.
In recent years, kratom has become an increasingly popular recreational drug around the world; consequently, this increase in popularity is matched by increasing concern over its potential to worsen the current opioid epidemic. As a result, further studies of kratom and its constituent compounds are necessary to better understand the mechanisms of action of these compounds and to evaluate possible therapeutic benefits of mitragynine or 7-hydroxymitragynine, present in kratom. Learn more in this application note.
Piperine, an alkaloid that gives black pepper its pungent taste (Piper nigrum), is also associated with several bioactivities and can be used as a spray in personal defense devices. The preparative separation and purification of piperine is usually performed by conventional methods. Among those methods are centrifugal partition chromatography (CPC) and flash chromatography. In this study, a crude extract of black pepper is used to purify piperine and to compare the performance of CPC versus flash chromatography - read more about the methods and results in this application note.